Evidence for Disturbed Regulation of Calciotropic Hormone Metabolism in Gitelman Syndrome
Little attention has been paid to interactions between circulating levels of calcium, PTH, and 1,25-dihydroxycholecalciferol [1,25(OH)2 D] and bone mineral density in primary renal magnesium deficiency. Plasma and urinary electrolytes, and circulating levels of calciotropic hormones were studied in 13 untreated patients with primary renal tubular hypokalemic alkalosis with hypocalciuria and magnesium deficiency. The blood ionized calcium concentration was significantly lower in patients than in controls.
by Herbert C. Mansmann, Jr., M.D.
Phosphorus is the second most abundant element of the human body. About 80% is in bones. The RDA is 700 mg/day, and the regular diet contains 1026 mg in women and 1455 in men. Phosphorus is present as phosphate in biologic systems. It is the concentration of elemental (or inorganic) phosphorus that is measured in the clinical laboratory, although the terms phosphorus and phosphate tend to be used interchangeably.
by Herbert C. Mansmann, Jr. M.D.
As a child in the 1920’s, Zinc (Zn) oxide was our antibiotic ointment for all sorts of skin conditions. As a pediatrician in the 1950’s, it was still the treatment of choice for infected diaper rashes. Recently Zn lozenges have become the treatment for symptoms of the common cold, although meta-analysis of multiple clinical studies has not borne this out as being effective. Most common cold viruses grow and reside in the nose, not in the throat, so this analysis should not be unsuspected. Yet Zn is very safe and if it seems to work for you, I would recommend that one continue to use the lozenges.
Medications and Supplements
The goal in treating Bartter and Gitelman patients is to correct the underlying electrolyte abnormalities and to prevent further wasting of these electrolytes. Below is a list of the most commonly used medications.
Table of Contents
- How does magnesium work for migraines ?
- Where do I go for magnesium testing and what type of test should I have?
- Why is my serum magnesium level normal but I have symptoms of hypomagnesemia?
- Who is at risk for hypomagnesemia?
- When is magnesium not good to take?
By Shawna Kopchu RN
Hypomagnesemia is a common imbalance in critically ill patients; yet it is frequently overlooked. (Perhaps one reason is that it is easily mistaken for potassium deficit, a condition with which it is often associated.) Magnesium deficit also occurs in less acutely ill individuals, such as those experiencing withdrawal from alcohol and those receiving nourishment after a period of starvation (as in tube feedings or total parental nutrition). Indeed, there are a number of clinical situations associated with hypomagnesemia; some of the more common etiological factors are described below.
By Herbert C. Mansmann Jr., M.D. and Shawna Kopchu RN
Choose the Right Magnesium
Choosing the right magnesium salt to take can be confusing. Each person has their own personal preference as to what they use based on manufacturer, price, quantity, dosage, ect. This page will help you understand each product based on dose, absorption rate, peak effect and side effects, ect. All of these products are considered dietary supplements and are available over the counter without a prescription. You can order all of them online or purchase them in any drugstore.
Americans may not be getting enough vitamins and minerals out of the food they eat. Over-processing, chemicals, preservatives and depleted soils have reduced the levels of natural vitamins and minerals we once received from our fruits and vegetables. Our nutrient levels are easily reduced by many factors in everyday life: stress, medications, coffee, alcohol and even exercising. As the body becomes depleted of these vitamins and minerals, it may extract them from other sources.